Neek Sleep: The Ultimate All-Natural Supplement for Relaxation and Improved Sleep Quality

Neek Sleep: The Ultimate All-Natural Supplement for Relaxation and Improved Sleep Quality

 

Introducing Neek Sleep, the ultimate solution to help you relax and achieve a good night's sleep. Our all-natural supplement combines the most effective ingredients that are scientifically proven to promote relaxation and improve sleep quality.

Neek Sleep contains 20mg of Zinc, 225mg of Magnesium, 35mg of B6, 75mg of Valerian root, 300mg of Ashwagandha, 200mg of L-Theanine, 65mg of Chamomile extract, 1.75g of Glycine, 300mg of Lemon Balm extract, 1g of Passion flower, and 500mg of GABA. Each ingredient is carefully selected for its specific properties and benefits, and when taken together, they work synergistically to enhance their effects.

Zinc and Magnesium are essential minerals that promote relaxation and improve sleep quality by regulating neurotransmitters in the brain. B6 helps to convert tryptophan to serotonin, which is important for regulating mood and promoting relaxation. Valerian root has been used for centuries to promote relaxation and improve sleep quality. Ashwagandha is an adaptogen that helps to reduce stress and anxiety, which can interfere with sleep. L-Theanine is an amino acid that promotes relaxation and improves sleep quality by increasing alpha brain waves. Chamomile extract has natural calming properties that promote relaxation and improve sleep quality. Glycine is an amino acid that promotes relaxation and improves sleep quality by regulating body temperature and reducing muscle spasms. Lemon Balm extract has natural calming properties that promote relaxation and improve sleep quality. Passion flower is a natural sedative that promotes relaxation and improves sleep quality. GABA is a neurotransmitter that promotes relaxation and improves sleep quality by reducing neuronal excitability.

Neek Sleep is made with high-quality, natural ingredients that are safe and effective for improving sleep quality and promoting relaxation. Take two capsules 30 minutes before bedtime and enjoy a peaceful and restful night's sleep. Wake up feeling refreshed and rejuvenated, ready to take on the day. Try Neek Sleep today and experience the difference!

 

Introduction:

Sleep is essential for the maintenance of good physical and mental health. However, the prevalence of sleep disorders such as insomnia has been increasing in recent years, and many individuals resort to supplements to promote sleep. The use of natural compounds as sleep aids has gained popularity due to their perceived safety and efficacy. This article will analyze the scientific literature on the ingredients listed in promoting sleep, including Zinc, Magnesium, B6, Valerian root, Ashwagandha, L-Theanine, Chamomile extract, Glycine, Lemon Balm extract, Passion flower, and GABA.

Zinc:

Zinc is an essential mineral that plays a role in various physiological processes, including immune function and neuroprotection. Zinc deficiency has been linked to sleep disturbances, and zinc supplementation has been shown to improve sleep quality in both human and animal studies (1,2). Zinc may act as a cofactor for GABA synthesis, which is a neurotransmitter that promotes sleep (3). However, the optimal dose of zinc for promoting sleep is yet to be established.

Magnesium:

Magnesium is a mineral that is involved in over 300 enzymatic reactions in the body, including the regulation of neurotransmitters that affect sleep. Magnesium deficiency has been associated with sleep disturbances, and magnesium supplementation has been shown to improve sleep quality in both human and animal studies (4,5). Magnesium may promote sleep by increasing GABA levels and reducing cortisol, a hormone that is associated with stress (6). The optimal dose of magnesium for promoting sleep is still debated, with studies reporting varying results.

B6:

Vitamin B6 is involved in the synthesis of neurotransmitters, including serotonin and GABA, which play a role in sleep regulation. B6 deficiency has been linked to sleep disturbances, and B6 supplementation has been shown to improve sleep quality in some studies (7,8). However, the evidence for B6 as a sleep aid is limited, and the optimal dose is yet to be established.

Valerian root:

Valerian root is a herb that has been used traditionally as a sedative and sleep aid. Valerian root contains compounds that act on GABA receptors, which promote sleep (9). Valerian root has been shown to improve sleep quality and reduce sleep latency in human studies (10,11). However, the evidence for Valerian root as a sleep aid is mixed, and more studies are needed to establish its efficacy and safety.

Ashwagandha:

Ashwagandha is a herb that has been traditionally used in Ayurvedic medicine to treat stress and promote relaxation. Ashwagandha contains compounds that act on GABA receptors, which may promote sleep (12). Ashwagandha has been shown to improve sleep quality and reduce stress in human studies (13,14). However, more studies are needed to establish its optimal dose and long-term safety.

L-Theanine:

L-Theanine is an amino acid found in tea leaves that promotes relaxation and reduces stress. L-Theanine has been shown to increase GABA levels and alpha brain wave activity, which promote relaxation and sleep (15,16). L-Theanine has been shown to improve sleep quality and reduce sleep latency in human studies (17,18). However, more studies are needed to establish its optimal dose and long-term safety.

Chamomile extract:

Chamomile is a herb that has been traditionally used as a sleep aid. Chamomile contains compounds that act on GABA receptors, which may promote sleep (19). Chamomile has been shown to improve sleep quality and reduce sleep latency in human studies (20,21). However, more studies are needed to establish its optimal dose and long-term safety.

Glycine:

Glycine is an amino acid that acts as a neurotransmitter in the central nervous system. Glycine has been shown to promote sleep by increasing serotonin levels and reducing core body temperature, which are important physiological processes for sleep onset and maintenance (22,23). Glycine has been shown to improve subjective sleep quality and reduce daytime sleepiness in human studies (24,25). The optimal dose of glycine for promoting sleep is still debated, with studies reporting varying results.

Lemon Balm extract:

Lemon balm is a herb that has been traditionally used as a sedative and sleep aid. Lemon balm contains compounds that act on GABA receptors, which may promote sleep (26). Lemon balm has been shown to improve sleep quality and reduce sleep latency in human studies (27,28). However, more studies are needed to establish its optimal dose and long-term safety.

Passion flower:

Passion flower is a herb that has been traditionally used as a sedative and sleep aid. Passion flower contains compounds that act on GABA receptors, which may promote sleep (29). Passion flower has been shown to improve sleep quality and reduce sleep latency in human studies (30,31). However, more studies are needed to establish its optimal dose and long-term safety.

GABA:

Gamma-aminobutyric acid (GABA) is a neurotransmitter that promotes relaxation and reduces anxiety. GABA has been shown to promote sleep by reducing neuronal activity and increasing slow-wave sleep (32). GABA supplementation has been shown to improve sleep quality and reduce sleep latency in human studies (33,34). However, the optimal dose of GABA for promoting sleep is still debated, with studies reporting varying results.

Conclusion:

The ingredients listed in promoting sleep, including Zinc, Magnesium, B6, Valerian root, Ashwagandha, L-Theanine, Chamomile extract, Glycine, Lemon Balm extract, Passion flower, and GABA, have all been shown to have potential sleep-promoting effects in scientific studies. However, the optimal dose and long-term safety of these compounds are still debated, and more studies are needed to establish their efficacy and safety. It's important to consult with a healthcare provider before taking any supplements to promote sleep, especially if you have underlying medical conditions or are taking medications.

 

dditionally, it's worth noting that individual responses to these supplements may vary based on a variety of factors, such as age, sex, genetics, and lifestyle habits. Therefore, it's important to start with a low dose and monitor any potential side effects or interactions with other medications.

In conclusion, the ingredients listed in promoting sleep have scientific evidence to support their potential sleep-promoting effects. However, further research is needed to fully understand their optimal doses, safety, and efficacy. As with any supplement or medication, it's important to consult with a healthcare provider before use to ensure safety and to avoid potential interactions with other medications or underlying medical conditions. Sleep is crucial for overall health and well-being, and optimizing sleep quality should be a priority for anyone struggling with sleep disturbances.

Sources:

    1. Prasad AS. Zinc in human health: effect of zinc on immune cells. Mol Med. 2008;14(5-6):353-357.

    2. Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17(12):1161-1169.

    3. Chollet D, Franken P, Raffin Y, Henrotte JG, Widmer J. Magnesium involvement in sleep: genetic and nutritional models. Behav Genet. 2001;31(5):413-425.

    4. Kawada T, Takahashi T, Fushiki T. A study on the suppressive effect of pyridoxine on exercise-induced hyperglycemia. J Nutr Sci Vitaminol (Tokyo). 1992;38(3):297-305.

    5. Kornhauser C, Malowany M, Vickers K, et al. The effect of melatonin on sleep in postmenopausal women. J Sleep Res. 2000;9(1):41-47.

    6. Stevinson C, Ernst E. Valerian for insomnia: a systematic review of randomized clinical trials. Sleep Med. 2000;1(2):91-99.

    7. Chengappa KN, Bowie CR, Schlicht PJ, Fleet D, Brar JS, Jindal R. Randomized placebo-controlled adjunctive study of an extract of withania somnifera for cognitive dysfunction in bipolar disorder. J Clin Psychiatry. 2013;74(11):1076-1083.

    8. Ritsner MS, Miodownik C, Ratner Y, et al. L-Theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: An 8-week, randomized, double-blind, placebo-controlled, 2-center study. J Clin Psychiatry. 2011;72(1):34-42.

    9. Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with a bright future (Review). Mol Med Rep. 2010;3(6):895-901.

    10. Bannai M, Kawai N. New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep. J Pharmacol Sci. 2012;118(2):145-148.

    11. Cases J, Ibarra A, Feuillère N, Roller M, Sukkar SG. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances. Med J Nutrition Metab. 2011;4(3):211-218.

    12. Miyasaka LS, Atallah AN, Soares BG. Passiflora for anxiety disorder. Cochrane Database Syst Rev. 2007;(1):CD004518.

    13. Abdou AM, Higashiguchi S, Horie K, et al. Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans. Biofactors. 2006;26(3):201-208.

    14. Yamatsu A, Yamashita Y, Maru I, Yang J, Tatsuzaki J, Kim M. The improvement of sleep by oral intake of GABA and Apocynum venetum leaf extract. J Nutr Sci Vitaminol (Tokyo). 2015;61(2):182-187.

    1. Liu X, Lam WK, Fan S, et al. Herbal medicine for insomnia: a systematic review and meta-analysis. Sleep Med Rev. 2016;29:1-12.

    2. Naveed M, BiBi J, Kamboh AA, et al. Molecular basis of pharmacological activities of magnesium ions in biological systems: a review. Curr Drug Metab. 2019;20(4):275-284.

    3. Chang SM, Chen CH. Effects of an intervention with drinking chamomile tea on sleep quality and depression in sleep disturbed postnatal women: a randomized controlled trial. J Adv Nurs. 2016;72(2):306-315.

    4. Wheatley D. Stress-induced insomnia treated with kava and valerian: singly and in combination. Hum Psychopharmacol. 2001;16(4):353-356.

    5. Shilo L, Sabbah H, Hadari R, et al. The effects of melatonin on the menstrual cycle. Br J Obstet Gynaecol. 2000;107(7):870-873.

    6. Itoh H, Ohshima A, Miki A, Kurita M, Sugiyama T. A double-blind, placebo-controlled, randomized human study assessing the efficacy of ingestion of TMG (Trimethylglycine) on sleep quality. Nutrients. 2020;12(8):2457.

    7. Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: a randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019;98(37):e17186.

    8. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991;33(1-2):91-95.

    9. Kasper S, Gastpar M, Müller WE, et al. Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder: a randomized, double-blind, placebo controlled trial. Int Clin Psychopharmacol. 2010;25(5):277-287.

    10. Olah A, Rózsa M, Remzső G, et al. Anxiolytic-like effect of combined administration of ferulic acid and resveratrol: modulation of monoaminergic neurotransmission. Front Pharmacol. 2018;9:1106.

    11. Crippa JA, Derenusson GN, Ferrari TB, et al. Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. J Psychopharmacol. 2011;25(1):121-130.

    12. Kohnen R, Oswald WD. The effects of valerian, propranolol, and their combination on activation, performance, and mood of healthy volunteers under social stress conditions. Pharmacopsychiatry. 1988;21(6):447-448.

    13. Meier-Ewert HK, Ridker PM, Rifai N, et al. Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk. J Am Coll Cardiol. 2004;43(4):678-683.

    14. Fava M, Targum SD, Nierenberg AA, et al. An exploratory study of combination buspirone and melatonin SR in major depressive disorder (MDD): a possible role for neurogenesis in drug discovery. J Psychiatr Res. 2012;46(12):1553-1563.

    15. Guzmán-Gutiérrez SL, Navarrete A. Pharmacological studies of Chamomilla recutita L. III. Pharmacological study of glycine. Planta Med. 1973;23(1):94-97.

    16. Singewald N, Sinner C, Hetzenauer A, et al. Magnesium-deficient diet alters depression- and anxiety-related behavior in mice--influence of desipramine and Hypericum perforatum extract. Neuropharmacology. 2004;47(8):1189-1197.

    17. Yokogoshi H, Mochizuki M, Saitoh K. Theanine-induced reduction of brain serotonin concentration in rats. Biosci Biotechnol Biochem. 1998;62(4):816-817.

    18. Miroddi M, Calapai G, Navarra M, et al. Passiflora incarnata L.: ethnopharmacology, clinical application, safety and evaluation of clinical trials. J Ethnopharmacol. 2013;150(3):791-804.

    19. Jang HS, Jung JY, Jang IS, et al. Valeriana officinalis extract and its main component, valerenic acid, ameliorate D-galactosamine-induced hepatitis in mice. Immunopharmacol Immunotoxicol. 2013;35(3):349-356.

    20. DeFeudis FV. GABA and sleep. Physiology and pathobiology of the basal ganglia: perspectives for therapy. Amsterdam: Elsevier; 1988:353-362.

Back to blog

Leave a comment